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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL1
All Species:
4.55
Human Site:
S269
Identified Species:
6.67
UniProt:
Q9UBP6
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9UBP6
NP_005362.3
276
31471
S269
P
V
L
Q
A
V
T
S
Q
T
S
L
P
G
H
Chimpanzee
Pan troglodytes
XP_001167352
301
34100
S294
P
V
L
Q
A
V
T
S
Q
T
S
L
P
G
H
Rhesus Macaque
Macaca mulatta
XP_001116496
301
34160
P294
P
V
L
Q
A
V
T
P
Q
T
S
L
P
G
H
Dog
Lupus familis
XP_849422
247
28132
P234
P
T
L
Q
A
M
T
P
S
P
T
P
L
G
H
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z120
268
30585
A260
I
Q
D
P
L
L
Q
A
V
T
P
N
P
T
L
Rat
Rattus norvegicus
XP_001054797
267
30550
A259
I
Q
D
P
L
L
Q
A
V
T
P
N
P
T
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516298
226
25512
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6NU94
273
31824
N263
A
V
F
R
R
I
E
N
R
T
F
I
Q
R
D
Zebra Danio
Brachydanio rerio
Q5XJ57
241
27917
R234
K
N
F
L
A
V
F
R
R
V
E
D
P
Q
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
O77263
256
29406
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q23126
256
30022
R249
G
K
W
P
A
I
F
R
R
L
P
N
P
A
L
Sea Urchin
Strong. purpuratus
XP_790960
406
47124
D399
A
V
F
R
R
I
P
D
P
W
T
A
A
T
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
B6SHG7
255
29101
R248
Q
T
F
Y
A
I
F
R
R
I
S
L
Q
E
E
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8GXB7
251
28800
Baker's Yeast
Sacchar. cerevisiae
Q12009
286
33373
C276
K
G
D
K
F
V
A
C
F
T
R
L
P
T
P
Red Bread Mold
Neurospora crassa
Q7RZC1
293
33715
R280
Q
K
H
V
A
L
F
R
R
L
E
D
P
Q
W
Conservation
Percent
Protein Identity:
100
90.6
90.6
81.5
N.A.
88
88.4
N.A.
64.8
N.A.
69.5
67.7
N.A.
47.4
N.A.
50.7
42.3
Protein Similarity:
100
91.3
91
83.6
N.A.
92.3
90.9
N.A.
72
N.A.
80
76.4
N.A.
59.7
N.A.
64.8
51.2
P-Site Identity:
100
100
93.3
46.6
N.A.
13.3
13.3
N.A.
0
N.A.
13.3
20
N.A.
0
N.A.
13.3
6.6
P-Site Similarity:
100
100
93.3
60
N.A.
26.6
26.6
N.A.
0
N.A.
46.6
26.6
N.A.
0
N.A.
26.6
26.6
Percent
Protein Identity:
N.A.
52.5
N.A.
50
46.8
48.8
Protein Similarity:
N.A.
68.4
N.A.
68.4
61.5
66.2
P-Site Identity:
N.A.
20
N.A.
0
26.6
13.3
P-Site Similarity:
N.A.
33.3
N.A.
0
33.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
13
0
0
0
50
0
7
13
0
0
0
7
7
7
0
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% C
% Asp:
0
0
19
0
0
0
0
7
0
0
0
13
0
0
7
% D
% Glu:
0
0
0
0
0
0
7
0
0
0
13
0
0
7
7
% E
% Phe:
0
0
25
0
7
0
25
0
7
0
7
0
0
0
0
% F
% Gly:
7
7
0
0
0
0
0
0
0
0
0
0
0
25
0
% G
% His:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
25
% H
% Ile:
13
0
0
0
0
25
0
0
0
7
0
7
0
0
0
% I
% Lys:
13
13
0
7
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
25
7
13
19
0
0
0
13
0
32
7
0
19
% L
% Met:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
0
0
0
0
0
7
0
0
0
19
0
0
0
% N
% Pro:
25
0
0
19
0
0
7
13
7
7
19
7
57
0
7
% P
% Gln:
13
13
0
25
0
0
13
0
19
0
0
0
13
13
0
% Q
% Arg:
0
0
0
13
13
0
0
25
32
0
7
0
0
7
0
% R
% Ser:
0
0
0
0
0
0
0
13
7
0
25
0
0
0
0
% S
% Thr:
0
13
0
0
0
0
25
0
0
44
13
0
0
25
13
% T
% Val:
0
32
0
7
0
32
0
0
13
7
0
0
0
0
0
% V
% Trp:
0
0
7
0
0
0
0
0
0
7
0
0
0
0
7
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _